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CU and SNC, which has its Space Systems division in Louisville, will announce details of the deal at a press conference on Monday.
Dream Chaser is the spacecraft SNC is developing to take astronauts to low-Earth orbit by 2017.
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The agreement with BioServe will allow SNC and BioServe to look at how BioServe services could be incorporated into Dream Chaser for future microgravity missions.