Brickell Biotech acquires exclusive rights for Japanese autoimmune disease treatment

BOULDER — Brickell Biotech Inc. (Nasdaq: BBI) announced Tuesday that it has acquired exclusive rights to develop and commercialize a portfolio of autoimmune drugs that were created by Japanese company Carna Biosciences Inc.

The drugs are oral Stimulator of Interferon Genes antagonists. STING is a protein that has a crucial role in human innate immunity. It induces the production of type-one interferon, which affects inflammation and immunoregulation.

However, the production of too much interferon can lead to inflammatory or autoimmune diseases such as lupus and rheumatoid arthritis. 

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The portfolio for which Brickell acquired the rights are STING antagonists, which means that they block interferon production to help treat autoimmune and inflammatory diseases.

“Our acquisition of Carna’s next-generation STING inhibitors represents a tremendous opportunity to expand our presence in immunology and inflammation and bring forward new treatment options for patients in need,” said Robert Brown, CEO of Brickell, in a prepared statement.